EMDataBank unified data resource for 3DEM

نویسندگان

  • Catherine L. Lawson
  • Ardan Patwardhan
  • Matthew L. Baker
  • Corey Hryc
  • Eduardo Sanz-García
  • Brian P. Hudson
  • Ingvar C. Lagerstedt
  • Steven J. Ludtke
  • Grigore Pintilie
  • Raul Sala
  • John D. Westbrook
  • Helen M. Berman
  • Gerard J. Kleywegt
  • Wah Chiu
چکیده

Three-dimensional Electron Microscopy (3DEM) has become a key experimental method in structural biology for a broad spectrum of biological specimens from molecules to cells. The EMDataBank project provides a unified portal for deposition, retrieval and analysis of 3DEM density maps, atomic models and associated metadata (emdatabank.org). We provide here an overview of the rapidly growing 3DEM structural data archives, which include maps in EM Data Bank and map-derived models in the Protein Data Bank. In addition, we describe progress and approaches toward development of validation protocols and methods, working with the scientific community, in order to create a validation pipeline for 3DEM data.

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عنوان ژورنال:
  • Nucleic acids research

دوره 44 D1  شماره 

صفحات  -

تاریخ انتشار 2016